Fibroids (uterine myomatosis, leiomyomas)
Fibroids (uterine leiomyomas) are benign tumours of the smooth muscle cells of the uterus. Women with fibroids can be asymptomatic, or may present with menorrhagia (30%), pelvic pain with or without dysmenorrhoea or pressure symptoms (34%), infertility (27%), and recurrent pregnancy loss (3%). Much of the data describing the relationship between the presence of fibroids and symptoms are based on uncontrolled studies that have assessed the effect of myomectomy on the presenting symptoms. One observational study (142 women) undertaken in the USA suggested that the prevalence of fibroids in infertile women can be as high as 13%, but no direct causal relationship between fibroids and infertility has been established.
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Aromatase inhibitors for uterine fibroids. (05 November 2013)
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