Non-steroidal anti-inflammatory drugs (NSAIDs) have anti-inflammatory, analgesic, and antipyretic effects, and they inhibit platelet aggregation. This review deals specifically with the use of NSAIDs for the treatment of the symptoms of musculoskeletal conditions. NSAIDs have no documented effect on the course of musculoskeletal diseases. NSAIDs inhibit the enzyme cyclo-oxygenase (COX), which has two known isoforms: COX-1 and COX-2. NSAIDs are often categorised according to their ability to inhibit the individual isoforms, with newer NSAIDs often predominantly inhibiting the COX-2 isoform and older NSAIDs often being less specific inhibitors.

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Safety of Nonsteroidal Anti-inflammatory Drugs in Major Gastrointestinal Surgery: A Prospective, Multicenter Cohort Study. ( 10 January 2017 )

Prophylactic non-steroidal anti-inflammatory drugs for the prevention of macular oedema after cataract surgery. ( 10 January 2017 )