Credits

Robert Andrew McIvor
Firestone Respiratory Institute
McMaster University
Hamilton, Ontario
Canada

Marcel Tunks
Assistant Professor of Medicine
Department of Medicine, McMaster University
Hamilton, Ontario
Canada

David Charles Todd
Assistant Professor of Medicine
Department of Medicine, McMaster University
Hamilton, Ontario
Canada

Competing interests

RAM has received honoraria for providing medical education and attending advisory board meetings for pharmaceutical companies involved in the management of COPD including Boehringer Ingelheim, AstraZeneca, GlaxoSmithKline, Pfizer, Nycomed, and Novartis. MT declares that he has no competing interests. DCT has received funding for investigator-initiated research in the past 3 years from the Ontario Thoracic Society and AstraZeneca Pharmaceuticals.
We would like to acknowledge the previous contributors of this review: Huib Kerstjens, Dirkje Postma, and Nick ten Hacken.